Depth-resolved fluorescence spectroscopy reveals layered structure of tissue.
نویسندگان
چکیده
A confocal fluorescence spectroscopy system is instrumented to study depth-resolved autofluorescence in biological tissue. The system provides the capability of optical sectioning with the maximal detectiondepth up to 120 m in the examined tissue samples. It was found that the topmost keratinizing epithelial layer produces strong fluorescence similar to collagen. The fluorescence signal from epithelial tissue between the keratinizing layer and stroma can be well resolved. The study results show that depth-resolved fluorescence spectroscopy has the potential to provide more accurate information for the diagnosis of tissue pathology.
منابع مشابه
Autofluorescence spectroscopy of epithelial tissues.
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عنوان ژورنال:
- Optics express
دوره 12 14 شماره
صفحات -
تاریخ انتشار 2004